Ctbp/bars
C-terminal-binding protein 1 also known as CtBP1 is a protein that in humans is encoded by the CTBP1 gene. CtBP1 is one of two CtBP proteins, the other protein being CtBP2. See more The CtBP1 protein was originally identified as a human protein that bound a PLDLS motif in the C-terminus of adenovirus E1A proteins. It and the related protein CTBP2 were later shown to function as transcriptional See more CTBP1 has been shown to interact with: • ACTL6B, • ARF, • EVI1 • FOXP2, See more • Human CTBP1 genome location and CTBP1 gene details page in the UCSC Genome Browser. • Overview of all the structural information available in the PDB for See more • Chinnadurai G (2002). "CtBP, an unconventional transcriptional corepressor in development and oncogenesis". Mol. Cell. 9 (2): 213–24. See more WebJul 1, 2003 · ( A ) Ribbon diagram of the t-CtBP/BARS dimer. The substrate- and the nucleotide-binding domains of each subunit are shown in similar green and red shades, respectively, with the swapping residues ...
Ctbp/bars
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WebApr 24, 2024 · CtBP loss triggers caspase 8-dependent apoptosis. Based on the prior demonstration of CtBP1/2 overexpression in ovarian cancer, and poor prognosis related to CtBP2 expression 8,9, we investigated ... WebCtBP3/BARS was the third protein of the CtBP (C-terminal binding protein) family to be identified. It was initially isolated as a 50-kDa cytosolic protein during the characterisation of the molecular targets of the toxin brefeldin …
WebJun 16, 2003 · The structural data show CtBP/BARS in a NAD(H)-bound dimeric form; the peptide binding maps the recognition site for DNA-binding proteins and histone … WebMar 1, 2006 · CtBP/BARS was originally identified as a ‘brefeldin A (BFA)-dependent ADP-ribosylation substrate’ during a search for factors that control membrane tubulation 15, …
WebDec 1, 2005 · Figure 2: Endophilin and CtBP/BARS do not have LPAAT activity and endophilin effects positive, rather than negative membrane curvature. a, E. coli that has … WebMar 1, 2006 · CtBP/BARS was originally identified as a ‘brefeldin A (BFA)-dependent ADP-ribosylation substrate’ during a search for factors that control membrane tubulation 15, 16. BFA is a fungal toxin that promotes the disassembly of the Golgi complex into tubules. Although BFA was known to block the GTP exchange factor for the small GTPase Arf, …
WebCtBP/BARS is a unique protein family in having quite diversified cellular functions, intercellular localizations, and developmental roles. ANGUSTIFOLIA (AN) is the sole homolog of CtBP/BARS from Arabidopsis thaliana, although it has plant AN-specific motifs and a long C-terminus.Previous studies suggested that AN would function in the nucleus …
WebCtBP/BARS), or cytosol treated with the affinity-purified anti-BARS/9 antibody (H, Cyt. anti-BARS Ab). Panel F shows the effects of BFA in intact cells (Control Intact Cells) for comparison. chimney valve suctionWebSep 18, 2024 · The C-terminal binding protein (CtBP) was first described as a phosphoprotein that binds specifically to the C-terminal end of the E1a adenovirus oncogene 1,2,3.These proteins were later found to ... grady henly decorators - lubbockWebHuman CtBP1 and rat CtBP/BARS have a high degree of homology (97% identity), differing in sequence primarily due to an amino terminal extension of CtBP1 not present in CtBP/BARS. 9, 14 Each of these structures … grady high school basketballWebMay 28, 2013 · BARS is structurally related to the D2-hydroxy acid dehydrogenase family and is a member of the CtBP family ().It is involved in two processes, one in the cell cytosol and the other in the nucleus ().In the cytosol, BARS controls the membrane-fission machinery that drives the formation of post-Golgi carriers (8, 9), endocytic fluid-phase … grady hendrix written worksWebMay 14, 2013 · Previous sequence comparison studies demonstrated that the plant AN gene encodes a protein related to C-terminal binding protein/brefeldin A ADP-ribosylated … grady hesterWebJul 12, 2016 · Membrane fission is an essential cellular process by which continuous membranes split into separate parts. We have previously identified CtBP1-S/BARS (BARS) as a key component of a protein … grady high school atlanta georgiaWebApr 1, 2002 · Sequence comparison between AN and CtBP/BARS from other organisms. Identical amino acids are marked in bold on a dark gray background and similar amino … grady high school atlanta name change